Comparisons / Agno vs LlamaIndex
Agno vs LlamaIndex: Which Agent Framework to Use?
Agno (formerly Phidata) is a lightweight Python framework for building agents. LlamaIndex started as a RAG framework — connect your data, query it with an LLM. Here is how they compare — paradigm, ecosystem, and the use cases each one is actually built for.
By the numbers
Agno
39.2k
5.2k
Python
Apache-2.0
2022-05-04
Agno (formerly Phidata)
LlamaIndex
48.3k
7.2k
Python
MIT
2022-11-02
Jerry Liu
GitHub stats as of April 2026. Stars indicate community interest, not necessarily quality or fit for your use case.
| Concept | Agno | LlamaIndex |
|---|---|---|
| Agent | `Agent(model=OpenAIChat(), instructions=[...])` class with `run()` method | `AgentRunner` with `AgentWorker`, or `ReActAgent` for tool-calling agents |
| Tools | Function tools via `@tool` decorator or built-in toolkits (web search, SQL, etc.) | `FunctionTool` for custom tools, `QueryEngineTool` to query an index as a tool |
| Agent Loop | `Agent.run()` handles tool dispatch internally, configurable via `show_tool_calls` | `AgentRunner.chat()` manages step-by-step execution via `AgentWorker` tasks |
| Memory / Knowledge | Knowledge bases (PDF, URL, vector DB) injected via `knowledge` param + built-in memory | — |
| Multi-Agent (Teams) | `Team` class with `agents` list, `mode` (sequential, parallel, coordinate), and shared memory | — |
| Storage | `SqlAgentStorage`, `PostgresAgentStorage` for persisting sessions and state | — |
| RAG Integration | — | `VectorStoreIndex` + `QueryEngineTool` — the agent can query your data as a tool call |
| Memory | — | `ChatMemoryBuffer` with token limit, or custom memory modules |
| Orchestration | — | `AgentRunner` step API for custom control flow, or multi-agent pipelines |
Agno vs LlamaIndex, head to head
Agno Agno (formerly Phidata) is a lightweight Python framework for building agents.
LlamaIndex LlamaIndex started as a RAG framework — connect your data, query it with an LLM.
Both wrap the same underlying agent pattern — an LLM call, a tool dispatch, a loop — in different abstractions. The choice between them is mostly about which mental model and ecosystem fits the team you have, not which one is technically more capable.
Pick Agno if
Pick Agno if agno adds value when you want a batteries-included agent with minimal boilerplate — especially for multi-modal agents or team orchestration. But each of its abstractions maps to a small piece of plain Python. If your agent is straightforward, writing it directly gives you full control with zero framework overhead. Agno is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; LlamaIndex would force you to translate.
Pick LlamaIndex if
Pick LlamaIndex if llamaIndex adds genuine value when your agent needs to query structured or unstructured data as part of its reasoning — that's the index-as-tool pattern, and it's well-executed. But if you're building a general-purpose agent that doesn't need RAG, the agent framework is overhead. The plain Python version of the agent loop is the same 60 lines either way. LlamaIndex is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; Agno would force you to translate.
What both add
Both Agno and LlamaIndex pull in a class hierarchy and a dependency tree to wrap what is, at the core, an HTTP POST in a while loop. If your use case is straightforward — one provider, a handful of tools, a single agent — the framework cost may exceed the framework benefit. The lesson below shows the same pattern in ~60 lines without either dependency.
Or build your own in 60 lines
Both Agno and LlamaIndex implement the same 8 patterns. An agent is a function. Tools are a dict. The loop is a while loop. The whole thing composes in ~60 lines of Python.
No framework. No dependencies. No opinions. Just the code.
Build it from scratch →