Comparisons / Agno vs Semantic Kernel

Agno vs Semantic Kernel: Which Agent Framework to Use?

Agno (formerly Phidata) is a lightweight Python framework for building agents. Semantic Kernel is Microsoft's enterprise SDK for building AI agents. Here is how they compare — paradigm, ecosystem, and the use cases each one is actually built for.

By the numbers

Agno

GitHub Stars

39.2k

Forks

5.2k

Language

Python

License

Apache-2.0

Created

2022-05-04

Created by

Agno (formerly Phidata)

github.com/agno-agi/agno

Semantic Kernel

GitHub Stars

27.6k

Forks

4.5k

Language

C#

License

MIT

Created

2023-02-27

Created by

Microsoft

github.com/microsoft/semantic-kernel

GitHub stats as of April 2026. Stars indicate community interest, not necessarily quality or fit for your use case.

ConceptAgnoSemantic Kernel
Agent`Agent(model=OpenAIChat(), instructions=[...])` class with `run()` method`ChatCompletionAgent` with `Kernel`, instructions, and service config
ToolsFunction tools via `@tool` decorator or built-in toolkits (web search, SQL, etc.)
Agent Loop`Agent.run()` handles tool dispatch internally, configurable via `show_tool_calls`
Memory / KnowledgeKnowledge bases (PDF, URL, vector DB) injected via `knowledge` param + built-in memory
Multi-Agent (Teams)`Team` class with `agents` list, `mode` (sequential, parallel, coordinate), and shared memory
Storage`SqlAgentStorage`, `PostgresAgentStorage` for persisting sessions and state
Tools / Plugins`KernelPlugin` with `@kernel_function` decorators, typed parameters
Planning`StepwisePlanner`, `HandlebarsPlanner` for multi-step decomposition
Memory`SemanticTextMemory` with embeddings and vector stores
Orchestration`Kernel.invoke()` with plugin resolution and filter pipeline
Multi-LanguageC#, Python, Java SDKs with shared abstractions

Agno vs Semantic Kernel, head to head

Agno Agno (formerly Phidata) is a lightweight Python framework for building agents.

Semantic Kernel Semantic Kernel is Microsoft's enterprise SDK for building AI agents.

Both wrap the same underlying agent pattern — an LLM call, a tool dispatch, a loop — in different abstractions. The choice between them is mostly about which mental model and ecosystem fits the team you have, not which one is technically more capable.

Pick Agno if

Pick Agno if agno adds value when you want a batteries-included agent with minimal boilerplate — especially for multi-modal agents or team orchestration. But each of its abstractions maps to a small piece of plain Python. If your agent is straightforward, writing it directly gives you full control with zero framework overhead. Agno is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; Semantic Kernel would force you to translate.

Full Agnocomparison →

Pick Semantic Kernel if

Pick Semantic Kernel if semantic Kernel earns its complexity in enterprise environments with Azure OpenAI, .NET backends, and existing Microsoft infrastructure. But the core agent pattern — LLM call, tool dispatch, loop — is identical to what you can build in 60 lines of Python. Semantic Kernel is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; Agno would force you to translate.

Full Semantic Kernelcomparison →

What both add

Both Agno and Semantic Kernel pull in a class hierarchy and a dependency tree to wrap what is, at the core, an HTTP POST in a while loop. If your use case is straightforward — one provider, a handful of tools, a single agent — the framework cost may exceed the framework benefit. The lesson below shows the same pattern in ~60 lines without either dependency.

Or build your own in 60 lines

Both Agno and Semantic Kernel implement the same 8 patterns. An agent is a function. Tools are a dict. The loop is a while loop. The whole thing composes in ~60 lines of Python.

No framework. No dependencies. No opinions. Just the code.

Build it from scratch →