Comparisons / Anthropic Agent SDK vs Semantic Kernel

Anthropic Agent SDK vs Semantic Kernel: Which Agent Framework to Use?

The Anthropic Agent SDK packages Claude Code's agent loop as a library. Semantic Kernel is Microsoft's enterprise SDK for building AI agents. Here is how they compare — paradigm, ecosystem, and the use cases each one is actually built for.

By the numbers

Anthropic Agent SDK

GitHub Stars

3.1k

Forks

582

Language

Python

License

MIT

Created

2023-01-17

Created by

Anthropic

Backed by

Google, Spark Capital

Production ready

Yes

github.com/anthropics/anthropic-sdk-python

Semantic Kernel

GitHub Stars

27.6k

Forks

4.5k

Language

C#

License

MIT

Created

2023-02-27

Created by

Microsoft

github.com/microsoft/semantic-kernel

GitHub stats as of April 2026. Stars indicate community interest, not necessarily quality or fit for your use case.

ConceptAnthropic Agent SDKSemantic Kernel
AgentClaude agent with built-in tools, MCP servers, and system prompt`ChatCompletionAgent` with `Kernel`, instructions, and service config
ToolsBuilt-in tools (`bash`, file read/write, web) + MCP server connections
Agent LoopSDK's internal agentic loop with automatic tool dispatch
Sub-AgentsAgents invoke other agents as tools via the SDK
Lifecycle Hooks18 hook events: pre/post tool call, message, error, etc.
MCP IntegrationOne-line MCP server config for Playwright, Slack, GitHub, etc.
Tools / Plugins`KernelPlugin` with `@kernel_function` decorators, typed parameters
Planning`StepwisePlanner`, `HandlebarsPlanner` for multi-step decomposition
Memory`SemanticTextMemory` with embeddings and vector stores
Orchestration`Kernel.invoke()` with plugin resolution and filter pipeline
Multi-LanguageC#, Python, Java SDKs with shared abstractions

Anthropic Agent SDK vs Semantic Kernel, head to head

Anthropic Agent SDK The Anthropic Agent SDK packages Claude Code's agent loop as a library.

Semantic Kernel Semantic Kernel is Microsoft's enterprise SDK for building AI agents.

Both wrap the same underlying agent pattern — an LLM call, a tool dispatch, a loop — in different abstractions. The choice between them is mostly about which mental model and ecosystem fits the team you have, not which one is technically more capable.

Pick Anthropic Agent SDK if

Pick Anthropic Agent SDK if the Anthropic Agent SDK's real value is packaging Claude Code's battle-tested agent loop with built-in tools and MCP integration. If you want a production agent that reads files, runs commands, and connects to services, it saves significant plumbing. For understanding how agents work, the plain version is more instructive. Anthropic Agent SDK is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; Semantic Kernel would force you to translate.

Full Anthropic Agent SDKcomparison →

Pick Semantic Kernel if

Pick Semantic Kernel if semantic Kernel earns its complexity in enterprise environments with Azure OpenAI, .NET backends, and existing Microsoft infrastructure. But the core agent pattern — LLM call, tool dispatch, loop — is identical to what you can build in 60 lines of Python. Semantic Kernel is the right fit when the tradeoffs in its intro line up with how your team actually wants to work day-to-day; Anthropic Agent SDK would force you to translate.

Full Semantic Kernelcomparison →

What both add

Both Anthropic Agent SDK and Semantic Kernel pull in a class hierarchy and a dependency tree to wrap what is, at the core, an HTTP POST in a while loop. If your use case is straightforward — one provider, a handful of tools, a single agent — the framework cost may exceed the framework benefit. The lesson below shows the same pattern in ~60 lines without either dependency.

Or build your own in 60 lines

Both Anthropic Agent SDK and Semantic Kernel implement the same 8 patterns. An agent is a function. Tools are a dict. The loop is a while loop. The whole thing composes in ~60 lines of Python.

No framework. No dependencies. No opinions. Just the code.

Build it from scratch →